Cognitive Changes in Brain Tumor Patients: Challenges, Rehabilitation, and Coping Strategies


Cognitive Changes in Brain Tumor Patients: Challenges, Rehabilitation, and Coping Strategies
Brain cancer patients often experience cognitive changes during treatment, which may affect their daily life, work, and overall quality of life.
With advances in medical treatments, the survival rate of brain tumor patients has improved. However, many patients still experience cognitive changes throughout the course of the disease and treatment. These changes can affect attention, memory, and executive functions, ultimately impacting daily life, work performance, and overall quality of life.
How do these cognitive changes occur? How can patients and caregivers effectively manage them? This article explores how brain tumors affect cognitive function, available rehabilitation approaches, and strategies to enhance quality of life, including the latest neurorehabilitation technique—Transcranial Magnetic Stimulation (TMS), which has shown promise in improving cognitive function.
How Do Brain Tumors Affect Cognitive Function?
Many brain tumor patients experience cognitive changes even at the time of diagnosis, and these changes may worsen due to treatment. The extent of cognitive decline depends on tumor location, disease progression, treatment methods, and other factors such as fatigue, anxiety, and depression.
Here are some of the most common cognitive challenges:

Reduced Attention and Difficulty with Multitasking
Patients may struggle with performing multiple tasks simultaneously, such as cooking while having a conversation or managing bills but forgetting their task when interrupted by a phone call.

Impaired Executive Function: Difficulties with Planning and Problem-Solving
Executive function is responsible for planning, organizing, and managing thoughts. Patients with executive dysfunction may:
- Have trouble scheduling daily activities or remembering important appointments
- Struggle to filter out distractions, leading to confusion
- Find decision-making challenging and feel overwhelmed by complex tasks

Memory Impairment: Difficulty Retrieving Information Rather Than Forgetting
Patients may forget recent conversations or misplace items, but unlike Alzheimer’s disease, their issue is mainly related to information retrieval rather than complete memory loss.

Language and Visuospatial Difficulties
- Language impairment: Patients may struggle with finding the right words, forming sentences, or understanding spoken language.
- Visuospatial impairment: They may have trouble navigating directions, reading maps, or judging distances when parking a car.
These challenges can impact independence and self-confidence, and they may increase the burden on caregivers. Thus, appropriate cognitive rehabilitation and coping strategies are crucial.
Impact of Treatment on Cognitive Function

Although brain cancer surgery, when combined with radiation therapy and chemotherapy, is effective in controlling tumors, it can also affect healthy brain cells, leading to short-term or long-term cognitive decline.
- Brain Cancer Surgery: For most brain tumor patients, surgery is the first and most common treatment option. However, when the tumor has unclear boundaries or invades normal brain tissue, the damage to brain tissue during surgery may result in cognitive changes.
- Radiation Therapy: May impact memory, processing speed, and cause fatigue. Some patients experience cognitive changes months or even years after treatment.
- Chemotherapy (Often Referred to as “Chemo Brain”): Can impair attention, executive function, and language fluency, especially in patients undergoing long-term treatment.
- Steroids and Other Medications: Certain medications used to reduce brain swelling, such as steroids, may cause temporary changes in mood and memory.
These side effects can lead to frustration, anxiety, or loss of confidence, but with the right cognitive rehabilitation and support, many patients can gradually regain function and improve their quality of life.
Cognitive Rehabilitation and Coping Strategies

1. Compensatory Strategies
External tools can help patients manage memory and attention difficulties:
- Use planners and digital reminders to keep track of daily tasks and appointments.
- Minimize distractions, such as turning off the TV or radio while reading or working.
- Focus on one task at a time, rather than multitasking.

2. Cognitive Rehabilitation
- Participate in cognitive training programs to strengthen memory and attention through repetitive exercises.
- Work with occupational therapists to develop personalized strategies for coping with cognitive changes.
- Engage in brain-stimulating activities such as crossword puzzles, Sudoku, reading, and journaling.

3. Brain Stimulation Therapy: Transcranial Magnetic Stimulation (TMS)
Transcranial Magnetic Stimulation (TMS) is a non-invasive neurorehabilitation technique that uses magnetic fields to stimulate brain activity, helping improve attention, memory, and mood.
Potential Benefits of TMS:
- Studies suggest that TMS can enhance neuroplasticity, improving cognitive function.
- It may serve as an adjunct therapy to reduce the effects of “chemo brain”.
- For patients with concurrent depression, TMS has been shown to boost mood and motivation.
Although TMS for brain tumor patients is still under research, many neurorehabilitation specialists are integrating it into comprehensive treatment plans, and it could become a promising option for improving brain function in the future.

4. Psychological and Pharmacological Interventions
- Psychotherapy: Cognitive-behavioral therapy (CBT) can help patients cope with anxiety and depression caused by cognitive changes.
- Medications: Certain drugs, such as dopaminergic or cholinergic agents, may improve attention and memory in some patients (should be assessed by a physician).
Supporting Patients in Adapting and Improving Quality of Life
Although brain tumors and treatments may affect cognitive function, with the right combination of rehabilitation, compensatory strategies, and emerging therapies like Transcranial Magnetic Stimulation (TMS), many patients can gradually regain cognitive abilities and enhance their quality of life.
Caregivers play a crucial role in providing understanding and patience, which are essential in helping patients adapt to these changes. By establishing routines, offering emotional support, and incorporating cognitive rehabilitation and new technologies, we can empower patients to navigate these challenges with hope and resilience, allowing them to continue leading fulfilling lives.